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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Mol Cancer Ther. 2017 Nov 15;17(1):26–38. doi: 10.1158/1535-7163.MCT-17-0580

Figure 2. MI-503 blocks sphere formation and cell migration in HCC cell lines.

Figure 2

A–D. Inhibition of cell migration in HepG2 (A, B) and Hep3B (C, D) cells upon treatment with MI-503 measured by the wound closure assay. Data in panels A and C represent mean of duplicates ± SD. * indicates p < 0.05, ** indicates p < 0.01. E, G. Quantification of spheres in the sphere formation assay performed in HepG2 (E) and Hep3B (G) cells upon 14 days of treatment with MI-503 and DMSO. Data represent mean of duplicates ± SD. F, H. Pictures of spheres upon treatment of HepG2 (F) and Hep3B (H) cells with MI-503 or DMSO.