Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Mol Cancer Ther. 2017 Nov 15;17(1):107–118. doi: 10.1158/1535-7163.MCT-16-0922

Figure 1. PDX models of CCA retain the KRAS sequence in codons 12 of the primary tumors from which they were derived.

Figure 1

(a) Representative PCR products from genomic DNA, using human specific KRAS primers that amplify a region of the KRAS gene encoding codons 12. NP-mouse = mouse normal pancreas DNA as template. Blank = no DNA control. (b) KRAS codon 12 sequence analyzed by Sanger Sequencing. PCR products were gel extracted, purified, and sequenced by the UAB Heflin Center Genomic Core. Results were visualized using Finch TV (detailed in Methods).