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The sequence of codon 12 of the KRAS gene was determined for F0 and F1 tumors.
| Specimen ID | KRAS codon 12 sequence change (F0) | Mutation conserved in PDX (F1) | Amino acid substitution |
|---|---|---|---|
| CCA1 | GGT | Yes | WT |
| CCA2 | GGT → GAT | Yes | G12D |
| CCA3 | GGT → GAT | Yes | G12D |
| CCA4 | GGT → GTT | Yes | G12V |
| CCA5 | GGT | Yes | WT |
