Table 2.

Functional Differences Between Mood State Groups

Cluster	Size	Peak Coordinates			Peak	Mean	mean % signal change
Number	(voxels)	x	y	z	t-stat	t-stat	Group A	Group B	Regions
Bipolar (A) vs. Healthy (B)
1	6188	−32	99	5	−4.70	−2.93	1.49	2.07	Visual Areas
Depressed (A) vs. Healthy (B)
1	4132	−18	103	5	−4.70	−2.64	1.44	2.27	Visual Areas
2	3469	−14	8	−7	−4.34	−2.77	0.07	0.25	R Thalamus
3	2741	13	18	8	−3.67	−2.76	0.05	0.23	L Thalamus
4	2355	−6	66	−33	−4.52	−3.05	0.003	0.16	Cerebellar Vermis
Manic (A) vs. Healthy (B)
1	15641	23	27	−9	−4.20	−2.49	−0.18	0.10	L Thalamus, Hippocampus, and Striatum
2	13865	−46	42	40	−3.40	−2.47	−0.15	0.14	R supramarginal gyrus, R Thalamus, Hippocampus, and striatum
3	7610	17	56	−38	−4.01	−2.78	−0.14	0.09	Cerebellar Vermis
4	6544	−19	101	−4	−5.34	−3.07	1.35	2.17	Visual Areas
Depressed (A) vs. Euthymic (B)
1	2579	16	50	8	−4.28	−2.59	−0.07	0.02	L corpus callosum and L posterior forceps
2	2486	−3	17	5	−3.44	−2.55	0.07	0.33	R Thalamus
Manic (A) vs. Euthymic (B)
1	2646	14	62	−35	−6.52	−2.41	−0.12	0.10	Cerebellar vermis and L cerebellum
2	2564	33	52	9	−8.05	−2.67	−0.18	0.01	L corpus callosum and L posterior forceps
3	2511	−3	18	1	−8.81	−2.53	−0.11	0.32	R Thalamus

L – Left, R - Right