Fig. 3.

Comparison of MERGE with four alternative methods in terms of the percentage of the significant associations replicated in the left-out test data. We discovered gene-drug associations within the data from all 30 samples, and we tested on a the 14 cell line samples, and b the data from the additional 12 refractory patient samples. Each gray line corresponds to a random ordering of all genes. We note that the x-axis in b contains a lower total number of genes; some of the genes existing in the microarray gene expression data from the 30 patient and cell line samples did not exist in the RNA-seq data from the 12 refractory patient samples