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. 2017 Dec 1;7(12):2526–2535.

Figure 3.

Figure 3

LncRNA HOXD-AS1 knockdown inhibited cell invasion ability in vitro and cell growth in vivo. (A, B) Transwell invasion assays were performed to determine the invasion ability in A375 and A2508 cells transfected with si-control, si-HOXD-AS1-1 (siRNA-1) and HOXD-AS1-2 (siRNA-2) or in B16 cells transfected with pcDNA3.1-vector (vector) and pcDNA3.1-HOXD-AS1 (HOXD-AS1). (C) The stable lncRNA HOXD-AS1 knockdown A375 cells were used for in vivo experiments. The nude mice carrying tumors from control and shRNA-HOXD-AS1 group were shown and (D) tumor volume curves were measured every 7 days after the injection of A375 cells. Data represented the mean ± SD. *, P<0.05.