Figure 3.

Within the tumor bearing group (open circles), tumor mass was significantly negatively correlated with systolic blood pressure (systolic BP, A) and left ventricle (LV) ∆pressure/∆time (B), but not LV end diastolic pressure (C). Closed circles represent the mean and SEM of the sham group (n=9, SEM in A is hidden by the mean circle) which are shown for comparison purposes only and are not factored into the correlation or regression calculations. Note that cardiac measurements were not obtained in one tumor bearing rat and that two tumor bearing rats had a tumor mass of 18.8 g and an LV ∆pressure/∆time of 6900 mmHg (i.e., two data points lie directly on top of one another) which is why there only appears to be seven data points in (B).