Table 1.

Cardiac and select hindlimb muscle mass

	Sham (n=9)	Tumor bearing (n=9)	p-value
Absolute muscle mass (mg)
Heart	854±26	723±30	<0.01*
Left ventricle	615±15	508±20	<0.01*
Right ventricle	239±17	215±18	0.35
Gastrocnemius	1843±28	1702±35	<0.01*
Soleus	164±6	166±4	0.80
Extensor digitorum longus	159±4	148±3	0.04*
Muscle mass normalized to femur length (mg/mm)
Heart/body mass	2.47±0.07	2.19±0.08	<0.01*
Left ventricle/femur length	15.4±0.3	12.5±0.5	<0.01*
Right ventricle/femur length	6.0±0.4	5.3±0.4	0.22
Gastrocnemius/femur length	46.2±1.0	42.0±0.7	<0.01*
Soleus/femur length	4.1±0.1	4.1±0.1	0.94
Extensor digitorum longus/femur length	4.0±0.1	3.6±0.1	0.02*
Muscle mass normalized to body mass (mg/g)
Left ventricle/body mass	1.80±0.03	1.54±0.05	<0.01*
Right ventricle/body mass	0.70±0.05	0.65±0.05	0.50
Gastrocnemius/body mass	5.46±0.07	5.16±0.10	0.03*
Soleus/body mass	0.48±0.01	0.50±0.02	0.31
Extensor digitorum longus/body mass	0.47±0.01	0.45±0.01	0.11

Data are mean ± SEM and were compared with unpaired Student’s t-tests.

^*indicate a statistically significant difference between groups.