Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 3;4(6):ENEURO.0269-17.2017. doi: 10.1523/ENEURO.0269-17.2017

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Toossi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 2. — Sleep-wake states, c-Fos, GABA_A, and AChM2 receptors in RFMes GABAergic neurons across groups. A, The percentage of time spent in wake during the 2 h preceding termination differed significantly across groups, being higher in SD as compared to SC and SR and lower in SR as compared to SC. B, The % of GAD+ neurons that were positively immunostained for c-Fos (+) differed significantly between groups, being greater in SD as compared to SC and SR. C, The % of GABA+ neurons which were positively immunostained for the GABA_AR (+) increased insignificantly following SD as compared to SC and SR (C1). The luminance of the GABA_AR immunofluorescence on GABA_AR+/GABA+ neurons differed significantly, being higher in SD as compared to SC (C2). D, The % of GAD+ neurons which were positively immunostained for AChM2R (+) differed significantly between groups, being higher in SD as compared to SC and SR (D1). The luminance of the AChM2R immunofluorescence on AChM2R+/GAD+ neurons differed significantly, being higher in SD as compared to SC and SR (D2). Note that the changes in GABARs and AChM2Rs on RFMes GABAergic neurons parallel the changes in % Wake and % c-Fos+/GAD+ across groups; * indicates significant difference of SD relative to SC; † indicates significant difference of SD relative to SR; § indicates significant difference of SR relative to SC (p < 0.05), according to post hoc paired comparisons following one-way ANOVA (Table 1).