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Effects of YY1 knockdown on T-bet and interferon-γ expression in peripheral blood mononuclear cells from autoimmune hepatitis type patients. PBMCs were isolated from 20 AIH-1 patients. PBMCs were transfected with YY1-siRNA or control-siRNA. Forty-eight hours after transfection, the mRNA expression levels of YY1, T-bet and IFN-γ were measured by real-time PCR. bP < 0.01 vs control. PBMCs: Peripheral blood mononuclear cell.
