Table 1.
Demographic data of the 469 patients with gastric cancer, n (%)
| Characteristics | CEA-Low group (n = 421) | CEA-High group ( n = 48) | P value |
| Age (yr), mean ± SD | 58.74 ± 10.98, 60 (20-83) | 60.4 ± 11.55, 61 (31-78) | |
| Gender | |||
| Female | 118 (28) | 12 (25) | 0.657 |
| Male | 303 (72) | 36 (75) | |
| Male-to-female ratio | 2.81:1 | 3:01 | |
| Family history | |||
| Positive | 8 (1.9) | 1 (2.01) | 0.930 |
| Negative | 413 (98.1) | 47 (97.99) | |
| HP infection status | |||
| Positive | 37 (8.8) | 5 (10.4) | 0.708 |
| Negative | 384 (91.2) | 43 (89.6) | |
| BMI (kg/m2) | |||
| Less than 18.5 | 28 (6.65) | 4 (8.33) | 0.358 |
| 18.5-24.99 | 304 (72.21) | 38 (79.17) | |
| More than 25 | 89 (21.14) | 6 (12.5) | |
| Differentiation degree | |||
| Well | 226 (53.7) | 22 (45.8) | 0.302 |
| Poor | 195 (46.3) | 26 (54.2) | |
| Location | |||
| Upper | 113 (26.8) | 16 (33.33) | 0.779 |
| Middle | 129 (30.64) | 10 (20.83) | |
| Lower | 168 (39.9) | 21 (43.75) | |
| Mixed | 11 (2.61) | 1 (2.08) | |
| Lauren classification | |||
| Intestinal type | 105 (24.94) | 10 (20.83) | 0.668 |
| Diffuse type | 270 (64.13) | 31 (64.59) | |
| Mixed type | 46 (10.93) | 7 (14.58) | |
| T category | |||
| T1a | 68 (16.2) | 4 (8.3) | 0.033a |
| T1b | 78 (18.5) | 5 (10.4) | |
| T2 | 89 (21.1) | 13 (27.1) | |
| T3 | 65 (15.4) | 14 (29.2) | |
| T4a | 116 (27.6) | 10 (20.8) | |
| T4b | 5 (1.2) | 2 (4.2) | |
| T1 | 146 (34.68) | 9 (18.75) | 0.026a |
| T2-4b | 275 (65.32) | 39 (81.25) | |
| Nerve invasion | |||
| Positive | 70 (16.6) | 11 (22.92) | 0.275 |
| Negative | 351 (83.4) | 37 (77.08) | |
| Vessel carcinoma embolus | |||
| Positive | 72 (17.1) | 15 (31.35) | 0.017a |
| Negative | 349 (82.9) | 33 (68.75) |
a
P < 0.05. HP: Helicobacter pylori; BMI: Body mass index; CEA: Carcinoembryonic antigen.