Table 2.
Multivariate analysis of correlation between lymph node metastasis and clinicopathological parameters of T1-stage colorectal cancer patients
| Clinicopathological characteristic | HR | P value |
95%CI |
|
| Lower bound | Upper bound | |||
| Gender, Male vs Female | 1.636 | 0.201 | 0.698 | 5.518 |
| Age (yr), < 60 vs ≥ 60 | 0.063 | 0.801 | 0.357 | 2.218 |
| Smoking No vs Yes | 0.880 | 0.348 | 0.529 | 6.077 |
| Preoperative CEA (ng/mL) < 5 vs ≥ 5 | 1.188 | 0.276 | 0.603 | 5.904 |
| Preoperative CA199 (ng/mL) < 9 vs ≥ 9 | 2.765 | 0.096 | 0.869 | 5.541 |
| Preoperative CA724 (ng/mL) < 2 vs ≥ 2 | 5.461 | 0.019 | 1.232 | 10.783 |
| Granulocyte absolute value, < 2.2 vs ≥ 2.2 | 0.004 | 0.951 | 0.285 | 3.797 |
| D-dimer < 0.21 vs ≥ 0.21 | 1.398 | 0.237 | 0.651 | 5.652 |
| Preoperative hemoglobin < 132 vs ≥ 132 | 0.437 | 0.508 | 0.249 | 1.992 |
| Tumor size (cm), < 3 vs ≥ 3 | 2.090 | 0.148 | 0.185 | 1.290 |
| Vascular invasion, No vs Yes | 8.461 | 0.004 | 2.358 | 81.596 |
| Tumor location, Rectum vs Colon | 0.264 | 0.607 | 0.485 | 3.444 |
| Differentiation degree, High/moderate vs Low | 4.204 | 0.040 | 1.057 | 11.956 |
| Tumor general type, Non-ulcer vs Ulcer | 0.686 | 0.407 | 0.556 | 4.239 |
| Tissue type, Non-adenocarcinoma vs Adenocarcinoma | 0.897 | 0.344 | 0.043 | 2.989 |