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. 2017 Nov 2;48(1):67–79. doi: 10.1007/s10519-017-9880-0

Table 1.

Recoding a phased genotype using three orthogonal terms

Phased genotype Freq Add Code Std add Dom code Std dom POE code Std POE
amoafa q2 0 -2p/q 0 -p/q 0 0
amoAfa pq 1 q-p/2pq 2p 1 − 1 -1/2pq
Amoafa pq 1 q-p/2pq 2p 1 1 1/2pq
AmoAfa p2 2 2q/p 4p-2 -q/p 0 0

The minor allele is A, with frequency p, major allele a with frequency q=1-p. Amo: maternally inherited A allele; Afa: paternally inherited A allele. “Freq” expected frequency of the genotype under Hardy–Weinberg equilibrium. “Add Code” additive coding of the phased genotype. “Std Add” standardized additive coding based on mean 2p and variance 2pq. “Dom Code” dominance coding of the phased genotype. “Std Dom” standardized dominance coding based on mean 2p2 and variance 4p2q2. “POE Code” parent-of-origin effect coding of the phased genotype. “Std POE” standardized parent-of-origin effect coding based on mean 0 and variance 2pq