Table 1. Biochemistry and anthropometric parameters in CAD cases vs. healthy controls in the entire study population reported in median (IQR)† or mean (SD)‡.
Parameters | Cases (n=83) | Controls (n=83) | P value |
---|---|---|---|
Age, years‡ | 51 (8.9) | 50 (8.9) | 0.49 |
Waist-Hip ratio‡ | 0.98 (0.05) | 0.95 (0.06) | 0.06 |
ApoA1, mg/dL† | 115 [100–128] | 136 [123–146] | <0.001 |
BMI‡ | 22.6 (2.6) | 23.3 (3.4) | 0.26 |
Systolic BP, mmHg† | 130 [110–140] | 120 [119–130] | 0.05 |
Diastolic BP, mmHg† | 80 [70–84] | 80 [76–81] | 0.46 |
Total cholesterol, mg/dL‡ | 188.5 [42] | 189 [33] | 0.93 |
Triglycerides, mg/dL† | 141 [94–190] | 123 [89–167] | 0.03 |
LDL-C, mg/dL‡ | 117 [33] | 123 [27] | 0.29 |
HDL-C, mg/dL† | 38 [36–42] | 43 [39–45] | 0.23 |
Non-HDL-C, mg/dL‡ | 146 [38] | 147 [33] | 0.82 |
VLDL-C, mg/dL† | 28 [19–38] | 25 [18–33] | 0.03 |
ApoB, mg/dL† | 85 [65–101] | 90 [73–102] | 0.31 |
ApoB/ApoA1† | 0.76 (0.6–0.9) | 0.68 (0.52–0.78) | 0.003 |
Lp(a), mg/dL† | 10.6 (4.6–25) | 14.5 (5.5–25) | 0.35 |
hs-CRP, mg/L† | 2.4 (1.2–5.3) | 1.6 (0.5–3.0) | 0.01 |
Lp-PLA2 conc, ng/mL§† | 253 [193–444] | 246 [193–333] | 0.05 |
Lp-PLA2 activity, nmol/min/mL† | 154 [138–183] | 166 [140–192] | 0.12 |
TG/HDL-C ratio† | 3.8 (2.2–5.3) | 3 [2–4] | 0.03 |
TC/HDL-C ratio† | 4.6 (3.8–5.6) | 4.7(4.0–5.5) | 0.44 |
†, Wilcoxon rank sum test for skewed distribution; reported in median (IQR); ‡, paired t-test for normal distribution; reported in mean (SD); §, concentration also known as Lp-PLA2 mass. Significant P values have been highlighted in italic. CAD, coronary artery disease; SD, standard deviation; IQR, interquartile range; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; VLDL-C, very low-density lipoprotein cholesterol; hs-CRP, high sensitivity C-reactive protein; Lp-PLA2, lipoprotein associated phospholipase A2.