Role of DEX on lung MPO activity and W/D ratio in lung and the total protein levels and the number of total cells, neutrophils, and macrophages in the BALF of CLP-stimulated ALI in WT rats. Rats were infused continuously with DEX or NS through the femoral vein cannula 30 min after CLP. Lung W/D ratio (A) and MPO activity (B) were evaluated in lung samples at 24 h after CLP. BALF was harvested at 24 h after CLP to determine the total protein levels (C) and the count of total cells (D), neutrophils (E), and macrophage (F). *P<0.05, #P<0.01 CLP vs. CLP+DEX. DEX, dexmedetomidine.