Role of DEX on pathological manifestations in lung samples in CLP-stimulated ALI. Rats were infused continuously with DEX or NS through the femoral vein cannula 30 min after CLP. Lung samples (n=10) were subjected to pathological assessment at 24 h following sepsis. Representative pathological manifestations of lung sample collected from different groups. (A) Control group, (B) DEX (10) group, (C) CLP group, (D) CLP+DEX (2.5) group, (E) CLP+DEX (5) group group, (F) CLP+DEX (10) group (H&E staining, magnification 200×). DEX, dexmedetomidine.