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. 2017 Dec 15;9(12):5245–5258.

Figure 8.

Figure 8

Roles of DEX on the pathological manifestations of CLP-stimulated ALI in WT and RAGE-/- rats. Rats were administration continuously with DEX (10 μg·kg-1·h-1) or NS through the femoral vein cannula 30 min after CLP. The lung W/D ratio (A) and MPO activity (B) were evaluated in lung samples obtained at 24 h after CLP. BALF was harvested to evaluate the total protein levels (C) and the count of total cells (D), neutrophils (E), and macrophage (F). *P<0.05 vs. CLP in WT or RAGE-/- rats, #P<0.05 vs. CLP+DEX in WT rats. DEX, dexmedetomidine.