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Roles of DEX on the levels of inflammatory molecules in lung samples and BALF from WT and RAGE-/- rats. Rats were infused continuously with DEX (10 μg·kg-1·h-1) or NS through the femoral vein cannula 30 min after CLP. Lung samples and BALF were harvested at 24 h after CLP to determine inflammatory molecules TNF-α (A, B), IL-1β (C, D), and IL-6 (E, F). *P<0.05 vs. CLP in WT or RAGE-/- rats, #P<0.05 vs. CLP+DEX in WT rats. DEX, dexmedetomidine.
