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AMD3100 can suppress lung cancer metastasis to brain in vivo. A. In vivo imaging biological processes in live nude mice. Three mice were picked out randomly from both AMD3100 treated group and control group of the established lung cancer metastasis model after 2, 4, and 5 weeks, respectively. Images were acquired by using a live-animal imaging system. B. The SDF-1 concentration in craniocerebral tissues was positively correlated with the number of brain metastatic foci.
