Table 2.
Sham | Ischemia | Hypoxia PC | GYKI PC | Hypoxia+GYKI PC | |
---|---|---|---|---|---|
Total exploration time in OR training (s) | 36.6±6.8 | 40.1±5.7 | 36.4±8.1 | 33.5±6.4 | 39.7±7.1 |
Total exploration time in OR test (s) | 39.3±5.2 | 42.5±6.2 | 39.6±6.8 | 41.7±8.9 | 39.9±6.7 |
Total exploration time in SR test (s) | 71.4±9.6 | 72.9±9.8 | 69.8±8.4 | 75.5±7.9 | 68.4±8.1 |
Open field Crossing (n) | 40.5±10.2 | 45.6±13.2 | 51.5±10.4 | 47.9±9.8 | 45.7±8.7 |
Open field Rearing (n) | 16.9±3.5 | 19.8±4.5 | 17.2±3.2 | 19.1±3.7 | 14.2±4.2 |
Data are expressed as mean ± SEM of the total exploration time in OR and SR. No significant difference in the exploratory and locomotor activities was shown between the Sham group, Ischemia group, hypoxia PC group, GYKI PC group, orhypoxia+GYKI PC group, indicating that the exploratory and locomotor activities were not influenced by the procedures. OR: object recognition; SR: social recognition; PC: preconditioning; GYKI: GYKI-52466. N=12 pre group.