Figure 3.

The dermal Vγ₄ ⁺ cells produced IL-17A, γ-IFN and IL-22 after application of IMQ cream. (A) Representation of IL-17A⁺ Vγ₄ ⁺ cells from mice with psoriasis-like skin inflammation on day 3 and 6. (B) The percent of IL-17⁺ cells on different days. (C) Representation of γ-IFN⁺ Vγ₄ ⁺ cells and (D) the percent of IFN-γ⁺ cells from mice with psoriasis-like skin inflammation on day 3 and 6. (E) The numbers of IL-22⁺ Vγ₄ ⁺ cells and (F) the percent of IL-22⁺ cells in mice treated with IMQ for 6 days. The values were calculated as the mean ± SEM (n=3), **p<0.01, ***p<0.001.