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. 2017 Dec 15;9(12):5585–5593.

Figure 2.

Figure 2

QL treatment diminishes isoproterenol (ISO)-induced cardiac fibrosis and cell death. A. Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) were increased in the ISO-induced mice which were reversed by QL treatment. B. Effects of QL on interstitial fibrosis assessed by masson trichrome staining, 400× magnifications. C. Western blotting analysis showed protein level of TGF-β, MMP-2 and MMP-9 was decreased by QL treatment. D. Western blotting analysis showed the Bcl-2/Bax ratio was decreased by QL in the ISO-induced mice. Data were analyzed by one-way ANOVA followed by Bonferroni’s post-hoc test and expressed as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001. n=6 per group.