Expression of PPARγ, p-AKT, AKT, p-ERK, ERK, p-P38, P38 in western blotting. A. The protein level of PPARγ and PGC1-α was down-regulated in the ISO-induced mice, which was reversed by QLQX treatment. B. QL has no effect on AKT, P-38 and ERK pathways. Data were analyzed by one-way ANOVA followed by Bonferroni’s post-hoc test and expressed as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001. n=6 per group.