Table 2.

Characteristics of WT and TRPC3/6/7^-/- mice 12 weeks after vehicle or STZ injection

Variable	WT		TRPC3/6/7-/-
	Veh	STZ	Veh	STZ
n	5	9	5	11
Blood glucose (mmol/l)	6.46±0.27	28.06±2.13aa	6.74±0.39	26.86±1.84bbb
Body weight (g)	27.37±1.73	23.40±0.62a	22.95±0.55a	18.62±0.87bb,cc
Urine volume (ml/24 h)	0.58±0.26	28.93±9.44aa	0.41±0.13	12.97±3.87bbb,c
Kidney/body weight ratio (%)	1.50±0.04	2.42±0.09aa	1.37±0.05	1.68±0.01b,c

Results are shown as means ± SEM.

^a p<0.05 vs. WT-Veh;

^aa p<0.001 vs. WT-Veh;

^b p<0.05 vs. TRPC3/6/7^-/--Veh.

^bb p<0.01 vs. TRPC3/6/7^-/--Veh.

^bbb p<0.001 vs. TRPC3/6/7^-/--Veh.

^c p<0.01, vs. WT-STZ.

^cc p<0.001, vs. WT-STZ.