Figure 4.
Salvianolic acid A (SalA) regulates the protein expression of apoptosis-related proteins, Nrf2 signaling, and MAPK signaling. A: Representative protein bands of Bax, Bcl-2, caspase-3 and caspase-9 expression in control, subarachnoid hemorrhage (SAH), and SalA-treated (10 and 50 mg/kg) groups were detected by western blot. B: Representative protein bands of Nrf2, HO-1 and NQO-1 expression in control, SAH, and SalA-treated (10 and 50 mg/kg) groups were detected by western blot. C: Representative protein bands of the proteins and the phosphorylation of the proteins in MAPK signaling in control, SAH, and SalA-treated (10 and 50 mg/kg) groups were detected by western blot. Values are represented as mean ± standard deviation (n = 5, each group). #P<0.05, ##P<0.01 compared to sham-operated group; *P<0.05, **P<0.01 compared to SAH group.