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Kaplan-Meier curves illustrating (A) overall survival and (B) recurrence-free survival among patients with invasive ductal carcinoma with respect to SPHK1 expression status. Patients whose tumors showed high SPHK1 expression had shorter overall survival times (P = 0.048) and recurrence-free survival (P < 0.001) compared to those showing low SPHK1 expression (log-rank test).
