FIG 1.

Overview of the features of the EBV genome and sequence diversity: alignment of 40 full-length genome sequences. The identity plot derived from this alignment is shown at the top and is colored as follows: dark green, 100% identity; light green, 30 to <100% identity; red, <30% identity. The black bar below represents a consensus sequence drawn from the alignment of the genomes of 40 EBV strains. Below the identity plot, EBV coding regions are shown in dark red, with arrows indicating the direction of the reading frame. The blue boxes indicate regions of the multigenome alignment that failed to align properly. The bold red box indicates the duplication in the LF3 ORF of the B95.8 reference genome that is missing in our patient cohort. These boxed regions were masked for phylogenetic and genetic distance calculations.