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Model for HCV, MYC, and NDRG1 interactions. HCV infection induces MYC expression probably via the activation of β-catenin and concomitantly decreases SGK1 and NDRG1 expression levels. The loss of SGK1 further diminishes the phosphorylation of NDRG1, and this results in increased lipid droplet formation. See Discussion for more details.
