TABLE 2.

Soluble CD4 binding to CD4-Ig and human monoclonal antibodies^a

^aCD4-Ig binding to soluble gp120 was measured by the ForteBio Octet QK^e platform (shown as K_Ds). MAb binding to gp120 was measured by ELISAs (shown as half-maximal effective concentrations [EC₅₀]). 1, color coding is as follows: red, <0.01 μg/ml; yellow, 0.01 to 0.1 μg/ml; orange, 0.1 to 1 μg/ml; and blue, >1 μg/ml. 2, 17b tested in the presence of sCD4 (3 μg/ml).