Table 2.
Description of the main studies in keratoconus (KC) management with soft contact lenses (SCLs).
| Author | Type of study | Type CL | Sample size (eyes) | Severity KC (number of cases) | Follow-up (months) (mean) | Mean age (years) | Sex (female/male) | HOA (μm) | UCVA (logMAR) (mean) | BCLCVA (logMAR) (mean) |
|---|---|---|---|---|---|---|---|---|---|---|
| Gumus and Kahraman [16] | Prospective comparative | SCL SiH (Toris K) | 50/20∗/30† | Moderate (50) | 2 Weeks | 24.5 | 32/18 | 0.71∗0.49† | NR | 0.00 |
| Fernandez-Velazquez [20] | Retrospective | SCL SiH (KeraSoft IC) | 94 | Mild (22) Moderate (46) Severe (6) |
10.3 | 35.5 | NR | NR | NR | 0.04 |
| Suzaki et al. [26] | Prospective cases series | SCL SiH | 30 | Moderate (30) | NR | 34.7 | 6/24 | 0.56 | NR | −0.11 |
| Sultan et al. [13] | Retrospective | SCL SiH (Toris K) | 64 | Mild-moderate (46) Severe (10) |
11.94 | 27.92 | 26/24 | NR | 0.83 | 0.20 |
| Yildiz et al. [17] | Prospective case series | SCL SiH | 24 | Mild (6) Moderate (13) Severe (5) |
4 | 31.7 | 4/8 | NR | NR | 0.10 |
| Yilmaz et al. [19] | Retrospective | SCL SiH | 60 | Moderate (60) | 24 | 27.3 | 18/23 | NR | 0.85 | 0.16 |
UCVA: uncorrected visual acuity; BCLCVA: best contact lens corrected visual acuity; HOA: high order aberration; CLIQ: contact lens impact on quality of life questionnaire; CXL: corneal cross-linking; NR: not reported. Mild KC (average sim K < 45 D); moderate (average sim K 45–52 D); severe (average sim K > 52 D). ∗No previous CXL. †Previous CXL.