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letter
. 2017 Dec 11;13:2631–2636. doi: 10.3762/bjoc.13.261

Scheme 2.

Scheme 2

Synthesis of AnhydroMurNAc. Conditions: (a) (±)-2-chloropropionic acid, NaH, dioxane, 45 °C to 90 °C, 2 h; (b) TrOTf, collidine, CH2Cl2, rt, 2 h; (c) (S)-2-chloropropionic acid, NaH, dioxane, 45 °C to 90 °C, 30 min; (d) trifluoroacetic acid, CHCl3, 0 °C to rt, 3 h.