Table 1. Advances, improvements and the number of miRNA-target interactions with different validation methods provided by miRTarBase 7.0.
| Features | miRTarBase 6.0 | miRTarBase 7.0 |
|---|---|---|
| Release date | 2015/09/15 | 2017/09/15 |
| Known miRNA entry | miRBase v20 | miRBase v21 |
| Known Gene entry | Entrez 2015 | Entrez 2017 |
| Species | 18 | 23 |
| Curated articles | 4966 | 8510 |
| miRNAs | 3786 | 4076 |
| Target genes | 22 563 | 23 054 |
| CLIP-seq datasets | 138 | 231 |
| Curated miRNA-target interactions | 366 181 | 422 517 |
| Text-mining technique to prescreen literature | NLP | Enhanced NLP |
| Download by validated miRNA-target sites | None | Yes |
| Browse by miRNA, gene, and disease | None | Yes |
| MTIs Supported by strong experimental evidences | ||
| Number of MTIs validated by ‘Reporter assay’ | 6694 | 9489 |
| Number of MTIs validated by ‘Western blot’ | 4580 | 7258 |
| Number of MTIs validated by ‘qPCR’ | 4645 | 8210 |
| Number of MTIs validated by ‘Reporter assay and Western blot’ | 3854 | 6032 |
| Number of MTIs validated by ‘Reporter assay or Western blot’ | 7439 | 10 581 |