Figure 2.

ReMap ChIP-seq binding pattern of 2829 datasets. A genome browser example of the ChIP-seq binding peak depth of the ReMap 2018 catalog compared to ReMap 2015 at the vicinity of the ELAC1 promoter (chr18:50,967,094-50,970,983). The tracks and peaks displayed are compacted to thin lines so the depth of ReMap 2018 bindings can be compared to ReMap 2015. A full and un-compacted screenshot is available as Supplementary Figures S2 and 3. On this location the ReMap 2018 catalog contains 1307 peaks, whereas the ReMap 2015 contains 229 peaks (ReMap 2015 lifted to GRCh38/hg38 assembly). The following genome tracks correspond to the GENCODE v24 Comprehensive Transcript Set and the 100 vertebrates base-wise conservation showing sites predicted to be conserved (positive scores in blue), and sites predicted to be fast-evolving (negative scores in red). A detailed view of the redundant peaks for a FOXA1 site is available in Figure 3.