Figure 1.

Data flow from LINCS DSGCs into the LDR and LDP. Data are submitted to the DCIC via different tools and then standardized, annotated, and loaded into the LDR. From the LDR, LINCS data are available via different mechanisms. Abbreviations: LINCS, Library of Integrated Network-based Cellular Signatures; DSGC, Data and Signature Generation Centers; DCIC, Data Coordination and Integration Center; HMS, Harvard Medical School; MEP LINCS, Microenvironment Perturbation LINCS Center; PCCSE, Proteomic Characterization Center for Signaling and Epigenetics; DToxS, Drug Toxicity Signature Generation Center; LDR, LINCS Data Registry; LDP, LINCS Data Portal; RESR, Representational State Transfer; API, Application Programming Interface.