Table 1. LINCS Data level definitions, descriptions and examples.

Data Level	Data Type	Description	Examples
1	Raw	Non-normalized, low-level, single-sample data obtained from assay instrumentation	RNA-Seq FASTQ, L1000 LXB
2	Processed	Raw data converted to a basic usable format through data processing, including presence or absence of specific molecular abnormalities	KiNativ binding profile, KINOMEScan relative inhibition
3	Normalized	Normalized, per sample data	L1000 Q2NORM, RNA-Seq raw counts
4	Signature	Quantified association across samples based on two or more characteristics	RNA-Seq Differential expression profile, L1000 GCTX file