Table 1. Comparison of chromatin interaction database.
Name of service | # of samples* | Hi-C heatmap | TAD annotation | Interaction table | Distance normalized interaction frequency | One-to-all interaction frequency | Dynamic browsing of visualization | Export and session management | Upload data or local installation | Data-type |
---|---|---|---|---|---|---|---|---|---|---|
3DIV | 80 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Hi-C | |
Chrom Contact | 6 | ✓ | ✓ | Hi-C | ||||||
HUGIN | 21 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Hi-C | ||
3Disease browser | 6 | ✓ | ✓ | ✓ | Hi-C | |||||
Hi-View | 2 | ✓ | ✓ | ✓ | ✓ | ✓ | Hi-C | |||
Hi-C data browser | 40 | ✓‡ | ✓ | ✓ | Hi-C, capture Hi-C, and ChIA-PET | |||||
HiGlass | 34† | ✓ | ✓¶ | ✓ | ✓ | Hi-C | ||||
Juicebox | 58† | ✓ | ✓¶ | ✓§ | ✓ | ✓ | Hi-C, capture Hi-C, and ChIA-PET | |||
WashU epigenome browser | 54† | ✓ | ✓ | ✓ | Hi-C, capture Hi-C, and ChIA-PET |
*Number of samples refer to only Hi-C experiments and multiple replicates were counted as one.
†HiGlass, Juicebox and WashU epigenome browser can visualize user’s own dataset.
‡Hi-C data browser provides Hi-C heatmap on different pages.
§Juicebox does not use pre-built one-to-all interaction data, but builds one-to-all interaction track in wiggle format on demand.
¶HiGlass and Juicebox load TADs annotations separately from interaction frequency data.