Table 2. Multivariate mixed model showing the association between change in sphingolipids of interest and change in verbal memory domain Z-score over 6 months of cardiac rehabilitation (CR) in patients with coronary artery disease (CAD).
Variable | b (SE) | p-value (p≤0.05)* |
---|---|---|
Years of education | 0.08 (0.02) | <0.0001* |
Waist circumference | 0.0005 (0.005) | 0.91 |
APOE4 allele | 0.19 (0.14) | 0.06 |
VO2peak | 0.003 (0.009) | 0.76 |
Sphingomyelin C16:0 | 0.76 (1.14) | 0.51 |
Sphingomyelin C20:1 | 0.95 (0.65) | 0.07 |
Sphingomyelin C24:1 | -0.46 (0.83) | 0.58 |
Dihydrosphingomyelin C20:0 | -1.13 (0.63) | 0.07 |
Ceramide C18:0 | -0.51 (0.25) | 0.04* |
Lactosylceramide C18:1 | 0.006 (0.48) | 0.99 |
Lactosylceramide C24:1 | 0.85 (0.45) | 0.06 |
Sphingosine-1-phosphate | -0.53 (0.17) | 0.002* |