Table 3.

Linear regression models for computerized cognitive scores in patients with impaired versus normal CVR – subgroup analyses

Subgroup	B coefficient ± SE*	p	B coefficient ± SE*	p	p for interaction
Carotid large-vessel disease	Yes (n = 229)	No (n = 183)
Executive function	−6.92 ± 1.81	<0.001	1.06 ± 1.98	0.59	<0.001
Memory	−5.23 ± 2.21	0.02	3.36 ± 2.68	0.21	0.03
Visual Spatial	−1.97 ± 2.35	0.40	0.38 ± 2.79	0.89	0.48
Attention	†	<0.001	†	0.40	0.09
Global cognitive score	−4.97 ± 1.50	<0.001	0.67 ± 1.84	0.72	0.02
Age (years)	>60 (n = 130)	≤60 (n = 285)
Executive function	−5.86 ± 2.81	0.04	−2.06 ± 1.5	0.17	0.23
Memory	−1.50 ± 2.79	0.59	−1.41 ± 2.15	0.51	0.99
Visual Spatial	−0.87 ± 3.45	0.80	−1.03 ± 2.11	0.63	0.87
Attention	†	0.11	†	0.01	0.78
Global cognitive score	−2.99 ± 2.36	0.21	−2.19 ± 1.34	0.10	0.87
Diabetes	Yes (n = 116)	No (n = 229)
Executive function	−5.10 ± 2.35	0.03	−2.35 ± 1.66	0.13	0.33
Memory	−1.01 ± 2.86	0.73	−1.90 ± 2.14	0.38	0.82
Visual Spatial	−1.21 ± 3.02	0.69	−1.13 ± 2.21	0.61	0.95
Attention	†	0.06	†	0.02	1.00
Global cognitive score	−2.80 ± 1.90	0.14	−2.30 ± 1.47	0.12	0.82

^*Adjusted for age, education, previous stroke, diabetes, hypertension and depressive symptoms.

^†Transformation of power of 4 was used for attention cognitive domains to approximate normality (hence, only p values are tabulated).