Table 1.
Demographic table for training and validation HCV-related cirrhosis cohorts
| Training cohort | Validation cohort | |||
|---|---|---|---|---|
| Controls | HCC cases | Controls | HCC cases | |
| N | 5611 | 451 | 5611 | 451 |
| Age at baseline (years) | 52.87 (7.28) | 54.67 (7.78) | 52.93 (7.39) | 54.89 (7.49) |
| Male | 5498 (97.99%) | 449 (99.56%) | 5501 (98.04%) | 447 (99.11%) |
| Female | 113 (2.01%) | 2 (0.44%) | 110 (1.96%) | 4 (0.89%) |
| Race | ||||
| White | 1954 (34.82%) | 173 (38.36%) | 2034 (36.25%) | 171 (37.92%) |
| Black | 623 (11.10%) | 54 (11.97%) | 576 (10.27%) | 60 (13.30%) |
| Other/Unknown | 3034 (54.07%) | 224 (49.67%) | 3001 (53.48%) | 220 (48.78%) |
| Number of AFP tests | ||||
| 1 | 1598 (28.48%) | 116 (25.72%) | 1598 (28.48%) | 138 (30.60%) |
| 2 | 1297 (23.12%) | 119 (26.39%) | 1240 (22.10%) | 106 (23.50%) |
| 3-4 | 1480 (26.38%) | 119 (26.39%) | 1524 (27.16%) | 120 (26.61%) |
| > 4 | 1236 (22.03%) | 97 (21.51%) | 1249 (22.26%) | 87 (19.29%) |
| Months between AFP tests | 11.67 (11.00) | 10.30 (10.10) | 11.83 (11.26) | 10.93 (10.89) |
| Baseline AFP in log2(ng/ml) | 2.92 (1.55) | 4.72 (2.78) | 2.95 (1.57) | 4.57 (2.95) |
| Baseline ALT in log2(ng/ml) | 6.14 (1.03) | 6.31 (0.91) | 6.16 (1.05) | 6.35 (0.88) |
| Baseline PLT in 1000’s | 147.97 (78.88) | 123.50 (66.06) | 148.51 (78.83) | 127.97 (76.08) |
For continuous variables we report means and standard deviations in parenthesis and for categorical variables we report the number in each group and percentages in parenthesis. Baseline was defined to be the date of the first AFP test