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. 2017 Oct 20;18(18):1643–1648. doi: 10.2217/pgs-2017-0103

Table 1. . Frequencies of heterogenous alleles of HLA-B loci.

HLA-B allele Frequency (%) Case with SJS/TEN vs general control Case with SJS/TEN vs tolerant control

  SJS/TEN (n = 12) General control (n = 236) Tolerant control (n = 17) Odds ratio (95% CI) p-value Odds ratio (95% CI) p-value
07:02 4 (1.7%)

07:05 12 (5.1%) 2 (11.8%)

13:01 6 (2.5%)

13:02 5 (2.1%)

15:02 8 (66.7%) 54 (22.9%) 4 (29.4%) 6.78 (1.96–23.38) 0.0021 6.5 (1.2–33.57) 0.029

15:12 6 (2.5%)

15:13 51 (21.6%) 2 (11.8%)

15:17 4 (1.7%)

15:21 2 (16.7%) 33 (14%) 1 (5.9%) 1.24 (0.26–5.89) 1 3.2 (0.26–40.05) 0.55

15:214 1 (8.3%) 1 (5.9%)

15:25 8 (3.4%)

15:32 4 (1.7%)

18:01 4 (33.3%) 29 (12.3%) 1 (5.9%) 3.59 (1.02–12.66) 0.06 8 (0.76–83.88) 0.12

18:02 8 (3.4%) 2 (11.8%)

18:33 1 (5.9%)

27:06 14 (5.9%)

35:01 2 (11.8%)

35:02 1 (5.9%)

35:03 11 (4.7%)

35:05 1 (8.3%) 39 (16.5%) 4 (23.5%) 0.42 (0.053–3.36) 0.49 0.29 (0.02–3.04) 0.37

35:32 1 (8.3%)

38:02 25 (10.6%)

40:01 17 (7.2%) 1 (5.9%)

40:06 4 (1.7%)

44:03 3 (25%) 42 (17.8%) 5 (29.4%) 0.46 (0.58–3.68) 0.7 0.8 (0.15–4.26) 1

44:13 1 (8.3%)

51:01 15 (6.4%) 2 (11.8%)

51:02 16 (6.8%)

52:01 5 (2.1%)

52:02 2 (11.8%)

56:02 4 (1.7%)

57:01 6 (2.5%)

58:01 27 (11.4%)

B others 15 (6.4%)

From Javanese and Sundanese General Population [25].

‘–’ no data available.

SJS/TEN: Stevens–Johnson syndrome/toxic epidermal necrolysis.