Table 2. . HLA-B75 serotype carrier frequency in carbamazepine-induced Stevens–Johnson syndrome/toxic epidermal necrolysis patients and normal controls.
HLA-B serotype | Frequency (%) | Case with SJS/TEN vs general control | Case with SJS/TEN vs tolerant control | ||||
---|---|---|---|---|---|---|---|
SJS/TEN (n = 12) | General control (n = 236) | Tolerant control (n = 17) | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
B75 | 10 (83.3%) | 87 (36.9%) | 5 (29.4%) | 8.56 (1.83–40) | 0.0018 | 12 (1.90–75.72) | 0.0078 |
SJS/TEN: Stevens–Johnson syndrome/toxic epidermal necrolysis.