Figure 5.

Effects of Compound C on serum cytokines in berberine-treated mice. Concanavalin A (Con A)-injected mice were pretreated with 100 mg/kg berberine with or without 20 mg/kg Compound C for three days. At 8 hours after Con A injection, the serum and liver samples were collected. Serum alanine aminotransferase (ALT) (A) and aspartate aminotransferase (AST) (B) levels were detected with an enzyme-linked immunoassay (ELISA). C is a photomicrograph of the mouse liver tissue section stained with hematoxylin and eosin (H&E) (magnification, ×200), data are expressed as the mean ±SD (n=6). ** P<0.01 vs. the control group, ^## P<0.01 vs. the Con A group, ^§§ P<0.01 vs. the Con A plus berberine group.