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Effects of Compound C on serum cytokines in berberine-treated mice. Concanavalin A (Con A)-injected mice were pretreated with 100 mg/kg berberine with or without 20 mg/kg of Compound C for three days. At 8 hours after Con A injection, the serum TNF-α (A), IFN-γ (B), IL-1β (C), IL-2 (D), and IL-10 (E) levels were detected with an enzyme-linked immunoassay (ELISA) (n=6). ** P<0.01 vs. the control group, ## P<0.01 vs. the Con A group, §§ P<0.01 vs. the Con A plus berberine group.
