TABLE 3.
Results of Bayesian Correction of Maternal Smoking in Estimating the Association Between Maternal Smoking and Children’s Risk for Oral Clefts, National Birth Defects Preventions Study, 1997–2003
| Model | Model Assumptions for Misclassification | CL/P ORa (95% Credible Interval) | CPO ORa (95% Credible Interval) |
|---|---|---|---|
| 1 | No misclassification | 1.3 (1.1–1.6) | 1.2 (1.0–1.5) |
| 2 | Misclassification with known sensitivity and specificity with maternal report as gold standard | 1.2 (0.9–1.5) | 1.0 (0.7–1.3) |
| 3 | Prior distributions on sensitivity and specificity, with maternal report as gold standard | 1.5 (1.1–2.1) | 1.1 (0.7–1.6) |
| 4 | Prior distributions on sensitivity and specificity, with cotinine levels used as gold standard | 1.6 (1.1–2.2) | 1.1 (0.7–1.7) |
a
OR is the posterior odds ratio.