TABLE 1.
Baseline characteristics (ITT population)
| PEG3350 + E (n = 48) | PEG4000 (n = 49) | |
| Age, y, mean (SD) | 5.5 (3.9) | 5.0 (3.3) |
| Males, n (%) | 22 (46%) | 18 (37%) |
| Weight, kg, mean (SD) | 22.9 (15.6) | 19.3 (7.9) |
| Height, cm, mean (SD) | 112.2 (27.7) | 109.3 (21.9) |
| Race | ||
| White, n (%) | 43 (90%) | 46 (94%) |
| Black, n (%) | 0 (0%) | 1 (2%) |
| Other, n (%) | 5 (10%) | 2 (4%) |
| <2 y of age: bowel movements per week, mean (SD) | 1.2 (1.1) | 1.6 (0.5) |
| ≥2 y of age: bowel movements on toilet per week, mean (SD) | 1.6 (0.8) | 1.2 (0.9) |
| ≥2 y of age: proportion of subjects with fecal incontinence (%) | 76% | 82% |
| ≥2 y of age: urinary incontinence (%) | 18% | 16% |
| Mean age at first complaints of constipation, mo, mean (SD) | 23.9 (30.5) | 21.4 (20.5) |
| Previous laxative treatment, n (%) | 34 (71%) | 38 (78%) |
ITT = intention-to-treat; PEG = polyethylene glycol; SD = standard deviation.