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. 2017 Dec 18;136(25):2406–2416. doi: 10.1161/CIRCULATIONAHA.117.029550

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© 2017 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 3. — Changes in expression of γ-H2AX and pATM in operators’ lymphocytes in response to radiation exposure during EVAR. A, Expression of γ-H2AX in operators’ lymphocytes before, immediately after, and 24 hours after open aortic repair (n=14) and EVAR (all IEVAR and BEVAR/FEVAR procedures grouped together [n=31]). B, Expression of pATM in operators’ lymphocytes before, immediately after, and 24 hours after open aortic repair (n=14) and EVAR (n=31). C, γ-H2AX expression during the peri-operative period of BEVAR/FEVAR (n=16) compared with IEVAR (n=15). D, pATM expression during the peri-operative period of BEVAR/FEVAR (n=16) compared with IEVAR (n=15). E, Correlation between fold change increase in γ-H2AX expression and DAP (n=31). F, Correlation between fold change increase in pATM levels and DAP (n=31). G, Correlation between fold change increase in γ-H2AX levels and fluoroscopy time (n=31). H, Correlation between fold change increase in pATM levels and fluoroscopy time (n=31). None of the operators studied wore leg shielding during these procedures. γ-H2AX indicates gamma H2AX; BEVAR, branched endovascular aortic repair; EVAR, endovascular aortic repair; FEVAR, fenestrated endovascular aortic repair; IEVAR, infrarenal endovascular aortic repair; and pATM, phosphorylated ataxia telangiectasia mutated protein. *P<0.05.