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Characteristics of Docetaxel Liposome Formulation and the Corresponding Placebo
| Formulation | Particle size (nm) | Polydispersity | Zeta potential (mV) | Entrapment efficiency (%) |
|---|---|---|---|---|
| Blank liposomes (without DTX and pshPFKFB3) | 87.3 ± 2.3 | 0.204 ± 0.009 | +21.6 ± 1.9 | – |
| DTX liposomes (From DoE) | 91.2 ± 9.4 | 0.269 ± 0.012 | +22.3 ± 1.8 | 87.3 ± 2.6 |
| DL | 105.6 ± 7.4 | 0.265 ± 0.021 | +17.8 ± 2.2 | 89.7 ± 4.1 |
| PSH-DL | 110.3 ± 8.3 | 0.285 ± 0.019 | +18.5 ± 0.9 | 88.9 ± 3.4 |
