Table 2.
Relative risks of fractures among apheresis donors in relation to cumulative number of apheresis donations.
Number of apheresis donations | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
|
||||||||||
1 – 8 | 9–24 | 25 – 49 | 50 – 99 | ≥ 100 | ||||||
All fractures | Events; incidence rate ratios (95% confidence interval) | |||||||||
Both sexes | 9 389 | 1.02 (0.99–1.06) | 4 795 | 1.00 (ref) | 2 731 | 1.00 (0.95–1.04) | 1 810 | 0.97 (0.92–1.02) | 1 041 | 0.99 (0.92–1.06) |
Women | 4 342 | 1.04 (0.99–1.09) | 2 158 | 1.00 (ref) | 1 180 | 1.00 (0.93–1.08) | 720 | 0.96 (0.88–1.05) | 358 | 1.00 (0.89–1.12) |
Women age 50 years or above | 1 762 | 1.08 (0.99–1.17) | 906 | 1.00 (ref) | 616 | 1.00 (0.91–1.11) | 462 | 0.99 (0.89–1.11) | 297 | 1.08 (0.94–1.24) |
Men | 5 047 | 1.01 (0.96–1.06) | 2 637 | 1.00 (ref) | 1 551 | 0.99 (0.93–1.05) | 1 090 | 0.97 (0.90–1.04) | 683 | 0.98 (0.90–1.07) |
Osteoporosis related fractures | ||||||||||
Both sexes | 3 814 | 1.06 (1.00–1.12) | 1 903 | 1.00 (ref) | 1 137 | 1.01 (0.94–1.09) | 804 | 1.03 (0.94–1.12) | 852 | 1.04 (0.96–1.13) |
Women | 2 246 | 1.07 (0.99–1.15) | 1 103 | 1.00 (ref) | 653 | 1.04 (0.94–1.14) | 420 | 1.01 (0.90–1.13) | 354 | 1.00 (0.88–1.13) |
Women age 50 years or above | 1 096 | 1.08 (0.97–1.19) | 564 | 1.00 (ref) | 412 | 1.07 (0.95–1.22) | 307 | 1.05 (0.92–1.21) | 203 | 0.99 (0.84–1.16) |
Men | 1 568 | 1.05 (0.97–1.15) | 800 | 1.00 (ref) | 484 | 0.98 (0.87–1.10) | 384 | 1.05 (0.93–1.18) | 498 | 1.07 (0.95–1.20) |