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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Transfusion. 2016 Nov 18;57(2):390–396. doi: 10.1111/trf.13907

Table 2.

Relative risks of fractures among apheresis donors in relation to cumulative number of apheresis donations.

Number of apheresis donations

1 – 8 9–24 25 – 49 50 – 99 ≥ 100
All fractures Events; incidence rate ratios (95% confidence interval)
  Both sexes 9 389 1.02 (0.99–1.06) 4 795 1.00 (ref) 2 731 1.00 (0.95–1.04) 1 810 0.97 (0.92–1.02) 1 041 0.99 (0.92–1.06)
  Women 4 342 1.04 (0.99–1.09) 2 158 1.00 (ref) 1 180 1.00 (0.93–1.08) 720 0.96 (0.88–1.05) 358 1.00 (0.89–1.12)
  Women age 50 years or above 1 762 1.08 (0.99–1.17) 906 1.00 (ref) 616 1.00 (0.91–1.11) 462 0.99 (0.89–1.11) 297 1.08 (0.94–1.24)
  Men 5 047 1.01 (0.96–1.06) 2 637 1.00 (ref) 1 551 0.99 (0.93–1.05) 1 090 0.97 (0.90–1.04) 683 0.98 (0.90–1.07)
Osteoporosis related fractures
  Both sexes 3 814 1.06 (1.00–1.12) 1 903 1.00 (ref) 1 137 1.01 (0.94–1.09) 804 1.03 (0.94–1.12) 852 1.04 (0.96–1.13)
  Women 2 246 1.07 (0.99–1.15) 1 103 1.00 (ref) 653 1.04 (0.94–1.14) 420 1.01 (0.90–1.13) 354 1.00 (0.88–1.13)
  Women age 50 years or above 1 096 1.08 (0.97–1.19) 564 1.00 (ref) 412 1.07 (0.95–1.22) 307 1.05 (0.92–1.21) 203 0.99 (0.84–1.16)
  Men 1 568 1.05 (0.97–1.15) 800 1.00 (ref) 484 0.98 (0.87–1.10) 384 1.05 (0.93–1.18) 498 1.07 (0.95–1.20)