Table 4.
Subgroup Analysis of the Association of Hemoglobin A1c and SCD.
| Cases, n | Controls, n | Multivariable Model,RR (95% CI) | P subgroup | P interaction | |
|---|---|---|---|---|---|
| Diabetes | |||||
| Yes | 72 | 72 | 1.31 (1.06–1.61) | 0.01 | 0.59 |
| No | 409 | 842 | 1.19 (0.92–1.54) | 0.18 | - |
| Diabetes or HbA1c ≥6.5% | |||||
| Yes | 97 | 101 | 1.27 (1.05–1.53) | 0.01 | 0.63 |
| No | 384 | 813 | 1.13 (0.74–1.73) | 0.56 | - |
| Cardiovascular Disease | |||||
| Yes | 195 | 354 | 1.15 (0.99–1.33) | 0.06 | 0.009 |
| No | 287 | 560 | 1.64 (1.31–2.06) | <0.001 | - |