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. Author manuscript; available in PMC: 2018 Sep 11.
Published in final edited form as: Toxicol Pathol. 2017 Sep 11;45(6):705–744. doi: 10.1177/0192623317728134

Figure 11. Representative image of forebrain ganglionic eminences at E12.5.

Figure 11

H&E-stained, transverse section, high magnification of ganglionic eminences in Figure 6B. Ganglionic eminences are transitory, embryonic brain structures that protrude into the lateral ventricles (LV) of the ventral telencephalon and guide tangential migration of neural cells. The lateral ganglionic eminence (LGE) gives rise to the striatum (caudate and putamen dorsally, nucleus of accumbens and olfactory tubercle ventrally), and the medial ganglionic eminence (MGE) gives rise to the globus pallidus and contributes to the population of GABAergic interneurons and oligodendrocytes of the developing cerebral cortex and other telencephalic structures. The caudal eminence (not pictured) differentiates into the amygdaloid body. Other abbreviations: H= Hippocampus; LT= lamina terminalis; TH= thalamus.